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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KCNC4
All Species:
10.3
Human Site:
T578
Identified Species:
25.19
UniProt:
Q03721
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03721
NP_001034663.1
635
69767
T578
R
R
A
L
R
R
S
T
T
R
D
R
N
K
K
Chimpanzee
Pan troglodytes
XP_001163681
635
69778
T578
R
R
A
L
R
R
S
T
T
R
D
R
N
K
K
Rhesus Macaque
Macaca mulatta
XP_001099902
632
69515
T575
R
R
A
L
R
R
S
T
T
R
D
R
N
K
K
Dog
Lupus familis
XP_547235
642
70645
G582
R
R
A
L
R
R
S
G
P
R
D
K
N
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q8R1C0
628
68637
P572
P
L
A
L
A
P
T
P
E
E
R
R
A
L
R
Rat
Rattus norvegicus
Q63734
625
68417
P569
P
L
A
S
A
P
T
P
E
E
R
R
A
L
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q7T199
516
58965
V460
T
I
A
L
P
V
P
V
I
V
S
N
F
N
Y
Frog
Xenopus laevis
P22739
499
56683
D443
P
K
I
P
S
S
P
D
L
Q
K
S
R
S
A
Zebra Danio
Brachydanio rerio
XP_001924019
603
67653
T547
L
S
P
G
E
R
W
T
L
R
C
S
R
N
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P17972
498
56491
Q441
R
R
V
L
P
V
E
Q
P
R
Q
P
R
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.9
89
N.A.
93.5
93.6
N.A.
N.A.
27.2
31.3
68.6
N.A.
40.1
N.A.
N.A.
N.A.
Protein Similarity:
100
99.6
98.9
90.8
N.A.
95.4
95.4
N.A.
N.A.
40.9
48.1
76.6
N.A.
55.2
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
80
N.A.
20
13.3
N.A.
N.A.
13.3
0
20
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
86.6
N.A.
33.3
26.6
N.A.
N.A.
13.3
13.3
26.6
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
70
0
20
0
0
0
0
0
0
0
20
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
40
0
0
0
0
% D
% Glu:
0
0
0
0
10
0
10
0
20
20
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
0
0
0
10
0
0
0
10
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
10
0
0
0
0
0
10
0
0
0
0
0
0
% I
% Lys:
0
10
0
0
0
0
0
0
0
0
10
10
0
40
40
% K
% Leu:
10
20
0
70
0
0
0
0
20
0
0
0
0
30
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
40
20
0
% N
% Pro:
30
0
10
10
20
20
20
20
20
0
0
10
0
0
10
% P
% Gln:
0
0
0
0
0
0
0
10
0
10
10
0
0
0
0
% Q
% Arg:
50
50
0
0
40
50
0
0
0
60
20
50
30
0
30
% R
% Ser:
0
10
0
10
10
10
40
0
0
0
10
20
0
10
0
% S
% Thr:
10
0
0
0
0
0
20
40
30
0
0
0
0
0
0
% T
% Val:
0
0
10
0
0
20
0
10
0
10
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _